1: With sodium hydroxide; hydrogen; palladium 10 on activated carbon in ethanol; water P=760.051 Torr; 48 h; 2: With hydrogenchloride in ethanol; water
参考文献
THE BRIGHAM AND WOMEN'S HOSPITAL, INC.; PRESIDENT AND FELLOWS OF HARWARD COLLEGE; YALE UNIVERSITY
Patent: WO2008/156701 A2, 2008 ;
Location in patent: Page/Page column 44; 45-46 ;
1: With piperidine; pyridine; hydrogen T=85°C; 3 h; 2: With palladium on activated charcoal in methanol; ethyl acetate T=20°C; P=836.056 Torr; 14 h; Further stages.;
参考文献
Kita; Higuchi; Yoshida; Iio; Kitagaki; Ueda; Akai; Fujioka
Journal of the American Chemical Society, 2001 , vol. 123, # 14 p. 3214 - 3222
