6-(4-氯苯基)吡嗪-3(2H)-酮合成路线 （共 12 条）
反应条件
bromine; trichlorophosphate in acetic acid
参考文献
American Cyanamid Company
Patent: US4092311 A1, 1978 ;
反应条件
1: phosphorus oxychloride / 4 h / 85 - 95 °C
2: hydrazine hydrate / butan-1-ol / 6 h / 100 °C
View Scheme
参考文献
Wermuth, Camille-Georges; Bourguignon, Jean-Jacques; Schlewer, Gilbert; Gies, Jean-Pierre; Schoenfelder, Angele; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 239 - 249
