6-对甲苯吡嗪-3(2H)-酮合成路线 （共 6 条）
反应条件
chlorosulphonyl isocyanate in chloroform T=55 - 60°C; 3 h;
参考文献
Srinivasan, T. N.; Rao, K. Rama; Satur, P. B.
Synthetic Communications, 1986 , vol. 16, # 5 p. 543 - 546
反应条件
copper dichloride in acetonitrile
0.5 h; Heating;
参考文献
Csende; Szabo; Bernath; Stajer
Synthesis, 1995 , # 10 p. 1240 - 1242
反应条件
hydrazine hydrate in ethanol
10 h; Reflux;
参考文献
El-Mobayed, Medhat M.; Hussein, Ahmed M.; Mohlhel, Wafia M.
Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 3 p. 534 - 537
反应条件
1: triphenyl(2-(p-toluoyl)ethyl)phosphonium bromide With hydrazine monohydrochloride in methanol; water
24 h; Heating;
2: carbon dioxide in methanol; water
Further stages.;
参考文献
Khachikyan
Russian Journal of General Chemistry, 2007 , vol. 77, # 6 p. 1134 - 1135
反应条件
1: 73 percent / KOH / H2O / 72 h / 20 °C
2: 50.5 percent / hydrazine hydrate / H2O / 4 h / Heating
View Scheme
参考文献
Khachikyan; Karamyan; Panosyan; Injikyan
Russian Chemical Bulletin, 2005 , vol. 54, # 8 p. 1982 - 1986
反应条件
ammonium hydroxide; hydrazine hydrate
1) heating, 2) water, reflux; Yield given. Multistep reaction;
参考文献
Coates; McKillop
Synthesis, 1993 , # 3 p. 334 - 342
