(Z)-4-十一烯-1-醇合成路线 （共 35 条）
反应条件
lithium aluminium tetrahydride in diethyl ether
a.) reflux while adding reagent b.) room temperature overnight c.) 30 min reflux;
参考文献
Vig, O. P.; Sharma, M. L.; Taneja, K. C.; Malik, Neera
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 10 p. 863 - 865
反应条件
[1,3-bis(diphenylphosphino) propane] dichloronickel(II) in benzene
T=70°C; 20 h;
参考文献
Wenkert, Ernest; Ferreira, Vitor F.; Michelotti, Enrique L.; Tingoli, Marco
Journal of Organic Chemistry, 1985 , vol. 50, # 5 p. 719 - 721
反应条件
1: 1.) lithium amide / 1.) liquid ammonia, 3 h; 2.) THF, 3 h
2: 90 percent / H2, quinoline / Lindlar's catalyst / hexane
View Scheme
参考文献
Sabharwal; Sharma; Vig
Journal of the Indian Chemical Society, 1989 , vol. 66, # 6 p. 411 - 412
反应条件
1: 1.) lithium amide / 1.) liquid ammonia, 3 h; 2.) THF, 3 h
2: 90 percent / H2, quinoline / Lindlar's catalyst / hexane
View Scheme
参考文献
Sabharwal; Sharma; Vig
Journal of the Indian Chemical Society, 1989 , vol. 66, # 6 p. 411 - 412
反应条件
2: 2.) CsF / 1.) MeOH 2.) THF
3: 1.) 9 BBN 2.) H2O2, NaOH / 1.) THF
4: 47 percent / ClCO2Me / acetone
5: Li2CuCl4 / tetrahydrofuran / -30 gradC, 2h, 0 gradC, 20h; organometallic educts, other temperature and reaction time
View Scheme
参考文献
Bac, Nguyen Van; Fall, Yagamare; Langlois, Yves
Tetrahedron Letters, 1986 , vol. 27, # 7 p. 841 - 844
反应条件
dilithium tetrachlorocuprate; oxonium in tetrahydrofuran
Yield given;
参考文献
Bac, Nguyen Van; Fall, Yagamare; Langlois, Yves
Tetrahedron Letters, 1986 , vol. 27, # 7 p. 841 - 844
反应条件
bis(cyclopentadienyl)titanium dichloride; lithium aluminium tetrahydride in tetrahydrofuran
Heating;
参考文献
Parenty, Arnaud; Campagne, Jean-Marc
Tetrahedron Letters, 2002 , vol. 43, # 7 p. 1231 - 1233
反应条件
1: 63 percent / dilithium tetrachlorocuprate / tetrahydrofuran / 1.) -78 deg C, 2 h, 2.) RT, 15 h
2: 99 percent / 5percent HCl / acetone / 6 h / Ambient temperature
3: 95 percent / diisobutylaluminum hydride / diethyl ether; toluene / 1.5 h / -10 °C
View Scheme
参考文献
Odinokov, V. N.; Galeeva, R. I.; Ishmuratov, G. Yu.; Kargapol'tseva, T. A.; Sokol'skaya, O. V.; et al.
Journal of Organic Chemistry USSR (English Translation), 1990 , vol. 26, # 11 p. 1986 - 1989
Zhurnal Organicheskoi Khimii, 1990 , vol. 26, # 11 p. 2299 - 2303
反应条件
1: 99 percent / 5percent HCl / acetone / 6 h / Ambient temperature
2: 95 percent / diisobutylaluminum hydride / diethyl ether; toluene / 1.5 h / -10 °C
View Scheme
参考文献
Odinokov, V. N.; Galeeva, R. I.; Ishmuratov, G. Yu.; Kargapol'tseva, T. A.; Sokol'skaya, O. V.; et al.
Journal of Organic Chemistry USSR (English Translation), 1990 , vol. 26, # 11 p. 1986 - 1989
Zhurnal Organicheskoi Khimii, 1990 , vol. 26, # 11 p. 2299 - 2303
反应条件
1: 90 percent / PBr3,Py / diethyl ether / a.) standing overnight b.) 2h reflux
2: 70 percent / benzene / 16 h / Heating
3: 78 percent / NaCl, H2O / dimethylsulfoxide / 8 h / 140 - 145 °C
4: 90 percent / LiAlH4 / diethyl ether / a.) reflux while adding reagent b.) room temperature overnight c.) 30 min reflux
View Scheme
参考文献
Vig, O. P.; Sharma, M. L.; Taneja, K. C.; Malik, Neera
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 10 p. 863 - 865
