(Z)-4-十一烯-1-醇合成路线 （共 35 条）
反应条件
1: 96 percent / triphenylphosphine, Br2 / CCl4 / 16 h / Ambient temperature
2: 1.) cuprous iodide, 2,2' bipyridyl / 1.) THF, 2 deg C, 10 min, 2.) THF, a) 2 deg C, 2 h, b) RT, 15 h
3: p-toluenesulfonic acid / methanol; H2O / 15 h / 20 °C
View Scheme
参考文献
Vig, O. P.; Sharma, M. L.; Sabharwal, Arun; Vohra, Neelam
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 1042 - 1044
反应条件
1: triethylamine / CH2Cl2 / 1) 0 deg C, 0.5 h, 2) RT, 6 h
2: LiBr / acetone / 5 h / Ambient temperature
3: 73 percent / dimethylsulfoxide / Ambient temperature
4: KOH / ethane-1,2-diol / 6 h / Heating
6: lithium aluminium hydride / diethyl ether / 3 h / Ambient temperature
7: 96 percent / pyridine / 24 h / Ambient temperature
View Scheme
参考文献
Kelkar, S. V.; Reddy, G. Bhaskar; Kulkarni, G. H.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 1-11 p. 980 - 981
反应条件
dipyridinium dichromate in dichloromethane
41 h; Ambient temperature;
参考文献
Wenkert, Ernest; Ferreira, Vitor F.; Michelotti, Enrique L.; Tingoli, Marco
Journal of Organic Chemistry, 1985 , vol. 50, # 5 p. 719 - 721
反应条件
1: triethylamine / CH2Cl2 / 1) 0 deg C, 0.5 h, 2) RT, 6 h
2: LiBr / acetone / 5 h / Ambient temperature
3: 73 percent / dimethylsulfoxide / Ambient temperature
4: KOH / ethane-1,2-diol / 6 h / Heating
6: lithium aluminium hydride / diethyl ether / 3 h / Ambient temperature
View Scheme
参考文献
Kelkar, S. V.; Reddy, G. Bhaskar; Kulkarni, G. H.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 1-11 p. 980 - 981
反应条件
1: 80 percent / PBr3 / pyridine; diethyl ether / 2 h / Heating
2: 1.) Mg, 1,2-dibromoethane; 2.) Li2CuCl4 / 1.) THF; 2.) THF, -10 deg C, 4 h
View Scheme
参考文献
Sabharwal; Sharma; Vig
Journal of the Indian Chemical Society, 1989 , vol. 66, # 6 p. 411 - 412
