2-(二甲基氨甲基)-3-羟基吡啶合成路线 （共 10 条）
反应条件
in water T=50°C; 4 h;
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP2100895 A1, 2009 ;
Location in patent: Page/Page column 74-75 ;
反应条件
in acetone T=0 - 20°C;
参考文献
ADOLOR CORPORATION
Patent: WO2008/63625 A2, 2008 ;
Location in patent: Page/Page column 77; 127 ;
WO 2008/063625 A2
反应条件
tri-n-butyl-tin hydride T=200°C; 0.5 h;
参考文献
Chao, Herbert S.-I.
Synthetic Communications, 1988 , vol. 18, # 11 p. 1207 - 1212
反应条件
in diphenylether T=250°C; 15 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 522 - 528
反应条件
pyridine
anschliessendes Behandeln mit CH3Br in Aceton;
参考文献
Hoffmann-La Roche
Patent: US2512732 , 1948 ;
Full Text Show Details
Stempel; Aeschlimann
Journal of the American Chemical Society, 1952 , vol. 74, p. 3323,3324
反应条件
pyridine
anschliessendes Behandeln mit CH3Br in Aceton;
参考文献
Stempel; Aeschlimann
Journal of the American Chemical Society, 1952 , vol. 74, p. 3323,3324
反应条件
pyridine
anschliessendes Behandeln mit CH3Br in Aceton;
参考文献
Hoffmann-La Roche
Patent: US2512732 , 1948 ;
Full Text Show Details
Stempel; Aeschlimann
Journal of the American Chemical Society, 1952 , vol. 74, p. 3323,3324
参考文献
Eisai RandD Management Co., Ltd.
Patent: EP1847535 A1, 2007 ;
Location in patent: Page/Page column 67 ;
EP 1847535 A1
参考文献
Sliwa,H.; Blondeau,D.
Journal of Heterocyclic Chemistry, 1976 , vol. 13, p. 419 - 420
参考文献
Stempel; Aeschlimann
Journal of the American Chemical Society, 1952 , vol. 74, p. 3323,3324
