1-(1,5-二甲基-1H-吡唑-4-基)乙酮合成路线 (共 9 条)
反应条件
2,2,2-trifluoroethanol T=0 - 20°C; 0.0833333 h; regioselective reaction;
参考文献
Alinezhad, Heshmatollah; Tajbakhsh, Mahmood; Zare, Mahboobeh
Journal of Fluorine Chemistry, 2011 , vol. 132, # 11 p. 995 - 1000
反应条件
hydrogenchloride in methanol 0.5 h; Ambient temperature;
参考文献
Menichi; Boutar; Kokel; et al.
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 1 p. 275 - 279
反应条件
in ethanol T=20°C; 24 h;
参考文献
Nishiwaki, Nagatoshi; Matsushima, Kazuo; Chatani, Miki; Tamura, Mina; Ariga, Masahiro
Synlett, 2004 , # 4 p. 703 - 707
反应条件
1: 38 percent / NaOEt / ethanol / 4 h / Heating 2: 25 percent / ethanol / 24 h / 20 °C View Scheme
参考文献
Synlett, , # 4 p. 703 - 707
反应条件
sodium methylate in methanol T=40°C; 18 h; Yield given. Yields of byproduct given;
参考文献
Journal of Chemical Research, Miniprint, , # 5 p. 1401 - 1443
反应条件
in methanol T=0°C; 4 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Heterocyclic Chemistry, , vol. 19, p. 1355 - 1361
反应条件
1: 5.6 g / aq.KOH / ethanol / 8 h / Heating 2: MeONa / methanol / 18 h / 40 °C View Scheme
参考文献
Journal of Chemical Research, Miniprint, , # 5 p. 1401 - 1443
反应条件
in diethyl ether 18 h; Ambient temperature;
参考文献
Journal of Chemical Research, Miniprint, , # 5 p. 1401 - 1443
反应条件
sodium hydroxide; bromine in water T=5 - 10°C; 2 h;
参考文献
Perevalov, V. P.; Manaev, Yu. A.; Andreeva, M. A.; Stepanov, B. I.
J. Gen. Chem. USSR (Engl. Transl.), 1985 , vol. 55, # 4 p. 882 - 885,787 - 789