4-(嘧啶-5-基)苯甲酸合成路线 （共 3 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethanol; water T=90°C; Suzuki coupling; Inert atmosphere;
参考文献
Holzer, Marcel; Ziegler, Sigrid; Neugebauer, Alexander; Kronenberger, Bernd; Klein, Christian D.; Hartmann, Rolf W.
Archiv der Pharmazie, 2008 , vol. 341, # 8 p. 478 - 484
反应条件
sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene in water; tert-butyl alcohol T=20°C; 2 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 3 p. 631 - 634
反应条件
1: Pd(Ph3P)4; aq. NaHCO3 / acetonitrile / 5 h / Heating 2: NaClO2; NaH2PO4; CH3CH=C(CH3)2 / 2-methyl-propan-2-ol; H2O / 2 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 3 p. 631 - 634
