2-氨基-5-氟吡啶合成路线

Takeuchi, Kumiko; Holloway, William G.; McKinzie, Jamie H.; Suter, Todd M.; Statnick, Michael A.; Surface, Peggy L.; Emmerson, Paul J.; Thomas, Elizabeth M.; Siegel, Miles G.; Matt, James E.; Wolfe, Chad N.; Mitch, Charles H.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 19 p. 5349 - 5352

70-23-53-溴丙酮酸乙酯+

21717-96-42-氨基-5-氟吡啶

367500-93-46-氟-咪唑并[1,2-a]吡啶-2-羧酸乙酯

参考文献

Rigby, Aaron; Sanganee, Hitesh; Springthorpe, Brian; Lawrence, Louise
Patent: US2002/77337 A1, 2002 ;

21717-96-42-氨基-5-氟吡啶

41404-58-42-溴-5-氟吡啶

参考文献

Jaeschke, Georg; Kolczewski, Sabine; Porter, Richard Hugh Philip; Schnider, Patrick; Vieira, Eric
Patent: US2007/78155 A1, 2007 ;
Location in patent: Page/Page column 29 ;
US 20070078155 A1

21717-96-42-氨基-5-氟吡啶

212268-12-72-氨基-5-氟-3-硝基吡啶

参考文献

AstraZeneca AB
Patent: US6265415 B1, 2001 ;
US 6265415 B1

21717-96-42-氨基-5-氟吡啶

823218-51-52-氨基-5-氟-3-吲哚吡啶

参考文献

AVEXA LIMITED
Patent: WO2008/77188 A1, 2008 ;
Location in patent: Page/Page column 136 ;