2-甲基-2-苯基丙烷-1-醇合成路线 （共 48 条）
反应条件
RhH2(O2COH)(P(i-Pr)3)2 in tetrahydrofuran
T=120°C; 20 h; Yield given. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Okano, Tamon; Kobayashi, Teruyuki; Konishi, Hisatoshi; Kiji, Jitsuo
Tetrahedron Letters, 1982 , vol. 23, # 47 p. 4967 - 4968
反应条件
1: NaH / tetrahydrofuran / 20 °C
2: LiAlH4 / tetrahydrofuran / Heating
View Scheme
参考文献
Nagao, Yoshimitsu; Tanaka, Satoru; Hayashi, Kazuhiko; Sano, Shigeki; Shiro, Motoo
Synlett, 2004 , # 3 p. 481 - 484
反应条件
1: 41 percent / CuF2*2H2O / diethyl ether / 12 h / Ambient temperature
2: 67 percent / MCPBA / dimethylformamide / 3 h / Ambient temperature
View Scheme
参考文献
Tamao, K.; Kakui, T.; Akita, M.; Iwahara, T.; Kanatani, R.; et al.
Tetrahedron, 1983 , vol. 39, # 6 p. 983 - 990
反应条件
in acetonitrile
T=55°C; other solvents (benzene, cyclohexane), other temperature, ClCH2COOH as a reagent, possible ways of the products formation; Product distributionRate constant;
参考文献
Leffler, J.E.; Barbas, J.T.
Journal of the American Chemical Society, 1981 , vol. 103, # 26 p. 7768 - 7773
反应条件
sodium methylate in ethanol; water
T=25°C; 45 deg C; Rate constant;
参考文献
Roberts, Donald D.
Journal of Organic Chemistry, 1984 , vol. 49, # 14 p. 2521 - 2526
反应条件
in acetone
24 h; Ambient temperatureIrradiation; Yield given;
参考文献
Pasternak, Mordechai; Morduchowitz, Abraham
Tetrahedron Letters, 1983 , vol. 24, # 33 p. 3439 - 3442
参考文献
Haller; Bauer
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1912 , vol. 155, p. 1583
Annales de Chimie (Cachan, France), 1918 , vol. <9> 9, p. 10
反应条件
1: sulfuric acid
2: sodium; alcohol
View Scheme
参考文献
Haller; Bauer
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1912 , vol. 155, p. 1583
Annales de Chimie (Cachan, France), 1918 , vol. <9> 9, p. 10
反应条件
(i) Mg, O2, Et2O, (ii) aq. H2SO4; Multistep reaction;
参考文献
Cadogan,J.I.G.; Foster,W.R.
Journal of the Chemical Society, 1961 , p. 3071 - 3076
反应条件
water
1) Et2O, -78 deg C to 20 deg C, 18 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Kauffmann, Thomas; Neiteler, Christel; Robbe, Sonja
Chemische Berichte, 1992 , vol. 125, # 11 p. 2409 - 2418
