4-氧-4h-苯并[d]嘧啶[2,1-b][1,3]噻唑-3-羧酸合成路线 （共 6 条）
反应条件
1: ethanol 2: diphenyl ether / 250 °C 3: aq. NaOH View Scheme
参考文献
Alaimo
Journal of Heterocyclic Chemistry, 1973 , vol. 10, # 5 p. 769 - 772
反应条件
1: diphenyl ether / 250 °C 2: aq. NaOH View Scheme
参考文献
Wade,J.J. et al.
Journal of Organic Chemistry, 1979 , vol. 44, # 11 p. 1811 - 1816
反应条件
hydrogen bromide Heating;
参考文献
Dunwell,D.W.; Evans,D.
Journal of the Chemical Society [Section] C: Organic, 1971 , p. 2094 - 2097
反应条件
sodium hydroxide; iodine; potassium iodide in 1,4-dioxane
参考文献
Sakamoto,M. et al.
Chemical and Pharmaceutical Bulletin, 1977 , vol. 25, p. 3360 - 3365
反应条件
1: benzene / Heating 2: aq. NaOH, KI, I2 / dioxane View Scheme
参考文献
Sakamoto,M. et al.
Chemical and Pharmaceutical Bulletin, 1977 , vol. 25, p. 3360 - 3365
反应条件
hydrogen bromide Heating;
参考文献
Alaimo
Journal of Heterocyclic Chemistry, 1973 , vol. 10, # 5 p. 769 - 772
