3-氨基甲酰-2-甲基咪唑并(1,2-a)吡啶合成路线 （共 2 条）
反应条件
1: With thionyl chloride in toluene T=100°C; 24 h; 2: With ammonia in tetrahydrofuran; water T=20°C; 3 h;
参考文献
MILLENNIUM PHARMACEUTICALS, INC.; TAKEDA PHARMACEUTICAL COMPANY LIMITED; BANNO, Hiroshi; HIROSE, Masaaki; KURASAWA, Osamu; LANGSTON, Steven, P.; MIZUTANI, Hirotake; SHI, Zhan; VISIERS, Irache; VOS, Tricia, J.; VYSKOCIL, Stepan
Patent: WO2010/90716 A1, 2010 ;
Location in patent: Page/Page column 321-322 ;
反应条件
pyridine; trifluoroacetic anhydride in tetrahydrofuran T=20°C; Cooling with ice;
参考文献
MILLENNIUM PHARMACEUTICALS, INC.; TAKEDA PHARMACEUTICAL COMPANY LIMITED; BANNO, Hiroshi; HIROSE, Masaaki; KURASAWA, Osamu; LANGSTON, Steven, P.; MIZUTANI, Hirotake; SHI, Zhan; VISIERS, Irache; VOS, Tricia, J.; VYSKOCIL, Stepan
Patent: WO2010/90716 A1, 2010 ;
Location in patent: Page/Page column 322 ;
