1,3,5-三苯基-1H-吡唑合成路线 （共 78 条）
反应条件
1: 91 percent / BuLi / hexane; dimethylsulfoxide; tetrahydrofuran / 12 h / 20 °C
2: 97 percent / Jones' reagent / acetone / 12 h / 0 °C
3: 68 percent / KOH; air / methanol / 12 h / Heating
View Scheme
参考文献
Chen; Lam, Yulin; Lai, Yee-Hing
Organic Letters, 2003 , vol. 5, # 7 p. 1067 - 1069
反应条件
1: 95 percent / Bu4NI; KI / dimethylformamide / 12 h / 20 °C
2: 91 percent / BuLi / hexane; dimethylsulfoxide; tetrahydrofuran / 12 h / 20 °C
3: 97 percent / Jones' reagent / acetone / 12 h / 0 °C
4: 68 percent / KOH; air / methanol / 12 h / Heating
View Scheme
参考文献
Chen; Lam, Yulin; Lai, Yee-Hing
Organic Letters, 2003 , vol. 5, # 7 p. 1067 - 1069
反应条件
1: 97 percent / Jones' reagent / acetone / 12 h / 0 °C
2: 68 percent / KOH; air / methanol / 12 h / Heating
View Scheme
参考文献
Chen; Lam, Yulin; Lai, Yee-Hing
Organic Letters, 2003 , vol. 5, # 7 p. 1067 - 1069
参考文献
Akasaka, Takeshi; Nakagawa, Masaru; Nomura, Yuko; Sato, Rikiya; Someno, Kazuo; Ando, Wataru
Tetrahedron, 1986 , vol. 42, # 14 p. 3807 - 3812
反应条件
1: triethylamine / methanol / 22 h / 0 - 20 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 - 20 °C / |Inert atmosphere
View Scheme
参考文献
Kawai, Hiroyuki; Yuan, Zhe; Tokunaga, Etsuko; Shibata, Norio
Organic Letters, 2012 , vol. 14, # 20 p. 5330 - 5333,4
反应条件
triethylamine in benzene
T=20°C; 48 h; Yield given;
参考文献
Namestnikov, V. I.; Trishin, Yu. G.; Tamm, L. A.; Christokletov, V. N.
J. Gen. Chem. USSR (Engl. Transl.), 1987 , vol. 57, # 5 p. 1202 - 1203,1076 - 1077
反应条件
1: 71 percent / piperidine / ethanol / 40 h
2: 80 percent / NaOEt / ethanol / Heating
3: 84 percent / NaOEt / ethanol / Heating
View Scheme
参考文献
Katritzky; Wang; Zhang; Voronkov; Steel
Journal of Organic Chemistry, 2001 , vol. 66, # 20 p. 6787 - 6791
反应条件
1: 71 percent / piperidine / ethanol / 40 h
2: 80 percent / NaOEt / ethanol / Heating
3: 84 percent / NaOEt / ethanol / Heating
View Scheme
参考文献
Katritzky; Wang; Zhang; Voronkov; Steel
Journal of Organic Chemistry, 2001 , vol. 66, # 20 p. 6787 - 6791
反应条件
1: 80 percent / NaOEt / ethanol / Heating
2: 84 percent / NaOEt / ethanol / Heating
View Scheme
参考文献
Katritzky; Wang; Zhang; Voronkov; Steel
Journal of Organic Chemistry, 2001 , vol. 66, # 20 p. 6787 - 6791
反应条件
1: 77 percent / acetic acid; ethanol / 0.67 h / Heating
2: 72 percent / pyridinium hexachloroantimonate / pyridine / 0.17 h
View Scheme
参考文献
Morkovnik, A. S.; Okhlobystin, O. Yu.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1985 , vol. 21, # 4 p. 461 - 464
Khimiya Geterotsiklicheskikh Soedinenii, 1985 , vol. 21, # 4 p. 551 - 554
