3-氨基二氢-2(3H)-呋喃酮盐酸盐(1:1)合成路线 (共 13 条)
反应条件
triethylamine in dichloromethane T=0 - 20°C; 12 h;
参考文献
Clerc, Jerome; Li, Nan; Krahn, Daniel; Groll, Michael; Bachmann, Andre S.; Florea, Bogdan I.; Overkleeft, Herman S.; Kaiser, Markus
Chemical Communications, 2011 , vol. 47, # 1 p. 385 - 387
反应条件
triethylamine in dichloromethane T=20°C; 17 h; Inert atmosphere;
参考文献
Sanchez, Adrian; Calderon, Ernesto; Vazquez, Alfredo
Synthesis (Germany), 2013 , vol. 45, # 10 art. no. SS-2012-M0583-OP, p. 1364 - 1372
反应条件
In alkalischen und in verduennten neutralen wss. Loesungen;
参考文献
Journal of the American Chemical Society, , vol. 71, p. 3399,3402
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride
参考文献
Horikawa, Manabu; Tateda, Kazuhiro; Tuzuki, Etsu; Ishii, Yoshikazu; Ueda, Chihiro; Takabatake, Tohru; Miyairi, Shinichi; Yamaguchi, Keizou; Ishiguro, Masaji
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 8 p. 2130 - 2133
反应条件
hydrogen bromide in acetic acid
反应条件
benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide in dichloromethane
参考文献
Dekhane, Mouloud; Douglas, Kenneth T.; Gilbert, Peter
Tetrahedron Letters, 1996 , vol. 37, # 11 p. 1883 - 1884
参考文献
Birnbaum; Greenstein
Archives of Biochemistry, 1953 , vol. 42, p. 212,214
Full Text Show Details
Kitagawa; Monobe
Journal of Biochemistry (Tokyo, Japan), 1933 , vol. 18, p. 333,337
Nippon Nogei Kagaku Kaishi, 1933 , vol. 9, p. 845,848
反应条件
methyl iodide in methanol; water
T=22°C; 48 h;
参考文献
Bothwell, Ian R.; Luo, Minkui
Organic Letters, 2014 , vol. 16, # 11 p. 3056 - 3059
反应条件
in 1,4-dioxane; hydrogenchloride; water
参考文献
Box, David; Colclough, David; Gillies, Iain; Loft, Michael Simon; Moore, Rebecca
Patent: US2004/87654 A1, 2004 ;
参考文献
Scripps Clinic and Research Foundation
Patent: US4415493 A1, 1983 ;