2-氰基-3,12-二氧代齐墩果-1,9(11)-二烯-28-酸甲酯合成路线 （共 13 条）
反应条件
1: 66 percent / NH2OH*HCl / ethanol; H2O / 1 h / Heating 2: 100 percent / NaOMe / methanol; diethyl ether / 0.75 h / 20 °C 3: 92 percent / DDQ / benzene / 0.5 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 22 p. 4233 - 4246
反应条件
1: 61 percent / NH2OH*HCl / aq. ethanol 2: 100 percent / sodium methoxide / methanol; diethyl ether 3: 1.) phenylselenenyl chloride, 2.) 30 percent aq. H2O2 / 1.) ethyl acetate, 2.) THF View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 19 p. 2711 - 2714
反应条件
lithium iodide in N,N-dimethyl-formamide
参考文献
Honda, Tadashi; Rounds, BarbieAnn V.; Gribble, Gordon W.; Suh, Nanjoo; Wang, Yongping; Sporn, Michael B.
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 19 p. 2711 - 2714
