(S)-3-(Boc-氨基)-5-苯基戊酸合成路线 （共 9 条）
反应条件
sodium periodate in methanol T=20°C;
参考文献
Journal of the American Chemical Society, , vol. 126, # 30 p. 9188 - 9189
反应条件
1.1: LDA / tetrahydrofuran / 1 h / -78 °C 1.2: 90 percent / tetrahydrofuran / 0.25 h / -78 °C 2.1: H2 / Pd/C / ethyl acetate / 20 °C 3.1: aq. (NH4)2Ce(NO3)6 / acetonitrile / 16 h / 0 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 39, # 6 p. 1063 - 1066
反应条件
1: H2 / Pd/C / ethyl acetate / 20 °C 2: aq. (NH4)2Ce(NO3)6 / acetonitrile / 16 h / 0 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 39, # 6 p. 1063 - 1066
反应条件
water; silver trifluoroacetate in tetrahydrofuran; triethylamine -25 deg C to RT, 4-5 h;
参考文献
Abele, Stefan; Guichard, Gilles; Seebach, Dieter
Helvetica Chimica Acta, 1998 , vol. 81, # 12 p. 2141 - 2156
反应条件
dipyridinium dichromate in N,N-dimethyl-formamide
参考文献
Tetrahedron Letters, , vol. 35, # 10 p. 1589 - 1592
反应条件
1: 4-DMAP / CH2Cl2 2: 1,3-dimethyl-2-phenyl-1,3,2-diazaphospholidine 3: 1.) 9-BBN, 2.) H2O2, NaOH / 1.) THF 4: PDC / dimethylformamide View Scheme
参考文献
Tetrahedron Letters, , vol. 35, # 10 p. 1589 - 1592
反应条件
1: 1.) 9-BBN, 2.) H2O2, NaOH / 1.) THF 2: PDC / dimethylformamide View Scheme
参考文献
Tetrahedron Letters, , vol. 35, # 10 p. 1589 - 1592
反应条件
1: 1.) i-BuOCOCl, N-methylmorpholine / 1.) THF, -20 deg C, 20 min; 2.) THF, Et2O, -5 deg C to RT, 4 h 2: 66 percent / H2O, CF3COOAg / tetrahydrofuran; triethylamine / -25 deg C to RT, 4-5 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 81, # 12 p. 2141 - 2156
反应条件
1: 440 mg / 1 h / Ambient temperature 2: 64 percent / aq. Na2CO3 / acetone / 2 h View Scheme
参考文献
Abele, Stefan; Guichard, Gilles; Seebach, Dieter
Helvetica Chimica Acta, 1998 , vol. 81, # 12 p. 2141 - 2156
