6-羟基-4-甲基-1-苯并呋喃-3(2H)-酮合成路线 （共 3 条）
反应条件
1: chloroacetyl chloride With AlCl3, aluminium chloride in nitrobenzene T=0°C; 2: 1-methyl-3,5-dihydroxy benzene in nitrobenzene T=0 - 20°C; 3: With sodium hydroxide in ethyl acetate
参考文献
WYETH LLC; AYRAL-KALOUSTIAN, Semiramis; MANSOUR, Tarek Suhayl; TSOU, Hwei-Ru; ZHANG, Nan; VENKATESAN, Aranapakam M.; DI, Li; KERNS, Edward H.
Patent: WO2010/30727 A1, 2010 ;
Location in patent: Page/Page column 93 ;
WO 2010/030727 A1
反应条件
potassium acetate in methanol 0.25 h; Heating;
参考文献
Mak, Marianna; Nogradi, Mihaly; Szoellosy, Aron
Tetrahedron, 2006 , vol. 62, # 35 p. 8425 - 8429
反应条件
1: ZnCl2; HCl gas / diethyl ether / cooling 2: H2O / Heating 3: 5.4 g / potassium acetate / methanol / 0.25 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 62, # 35 p. 8425 - 8429
