1-(4-甲氧基苄基)-哌嗪双盐酸盐合成路线 (共 1 条)
反应条件
1: With potassium hydroxide; N-hexadecyl-N,N,N-trimethylammonium bromide in water; benzene T=70°C; 1 - 3 h; Heating / reflux; 2: With hydrogenchloride in ethanol pH=3;
参考文献
Shanghai Institute of Pharmaceutical Industry
Patent: US2005/267121 A1, 2005 ;
Location in patent: Page/Page column 10 ;