6-氟-4(1H)-喹啉酮合成路线 （共 3 条）
反应条件
Dowtherm® A 0.166667 h; Heating / reflux;
参考文献
GLAXO GROUP LIMITED
Patent: WO2004/14361 A1, 2004 ;
Location in patent: Page/Page column 41 ;
反应条件
water in diphenylether T=260°C; P=15001.5 Torr; 0.333333 h; microwave irradiation;
参考文献
Adams, Martina M.; Bats, Jan W.; Nikolaus, Nadja V.; Witvrouw, Myriam; Debyser, Zeger; Engels, Joachim W.
Collection of Czechoslovak Chemical Communications, 2006 , vol. 71, # 7 p. 978 - 990
反应条件
phosphorus tribromide in DMF (N,N-dimethyl-formamide); water
T=0 - 20°C; 1.08333 h;
参考文献
GLAXO GROUP LIMITED
Patent: WO2004/14361 A1, 2004 ;
Location in patent: Page/Page column 41 ;
