2,2,2-三氯-1-(1-甲基-1H-吡咯-2-基)-乙酮合成路线 （共 32 条）
反应条件
1: HNO3, Ac2O / -40 - 20 °C 2: 47 percent / NaOMe / 2 h / Ambient temperature View Scheme
参考文献
Journal of the American Chemical Society, , vol. 118, # 26 p. 6141 - 6146
反应条件
1: 81 percent / N-bromosuccinimide / CH2Cl2 / 18 h / -10 - 20 °C 2: 93 percent / methanol / 1 h 3: 99 percent / K3PO4; N,N'-dimethylethylenediamine / CuI / dioxane / 48 h / 110 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 69, # 23 p. 8151 - 8153
反应条件
1: 2 N sodium hydroxide / 1 h / 65 °C 2: oxalyl chloride / toluene / 1 h / 50 °C View Scheme
参考文献
Groot, J. A. de; Steen, R. van der; Fokkens, R.; Lugtenburg, J.
Recueil: Journal of the Royal Netherlands Chemical Society, 1982 , vol. 101, # 6 p. 219 - 223
反应条件
nitric acid; acetic anhydride T=-5°C; 3 h;
参考文献
Badaea, Concepcion; Souard, Florence; Vicent, Cristina
Journal of Organic Chemistry, 2012 , vol. 77, # 23 p. 10870 - 10881
反应条件
nitric acid in acetic anhydride 2 h; Ambient temperature;
参考文献
Moore, Michael J. B.; Cuenca, Francisco; Searcey, Mark; Neidle, Stephen
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 18 p. 3479 - 3488
反应条件
in tetrahydrofuran T=20°C; 1 h;
参考文献
Essa, Ali H.; Lerrick, Reinner I.; Tuna, Floriana; Harrington, Ross W.; Clegg, William; Hall, Michael J.
Chemical Communications, 2013 , vol. 49, # 27 p. 2756 - 2758
反应条件
in tetrahydrofuran T=20°C; 1 h;
参考文献
Chemical Communications, , vol. 49, # 27 p. 2756 - 2758
反应条件
in tetrahydrofuran T=20°C; 1 h;
参考文献
Chemical Communications, , vol. 49, # 27 p. 2756 - 2758
反应条件
in tetrahydrofuran T=20°C; 1 h;
参考文献
Chemical Communications, , vol. 49, # 27 p. 2756 - 2758
反应条件
in tetrahydrofuran T=20°C; 1 h;
参考文献
Chemical Communications, , vol. 49, # 27 p. 2756 - 2758
