2-(4-甲基苯氧基)苯甲酸合成路线 （共 16 条）
反应条件
1: 85 percent / KMnO4, KOH 2: 90 percent / polyphosphoric acid / 4 h / 180 - 200 °C View Scheme
参考文献
Anschuetz; Stoltenhoff; Voeller
Chemische Berichte, 1925 , vol. 58, p. 1738
参考文献
Hellwinkel, Dieter; Bohnet, Siegbert
Chemische Berichte, 1987 , vol. 120, p. 1151 - 1174
反应条件
1: 85 percent / KMnO4, KOH 2: 90 percent / polyphosphoric acid / 4 h / 180 - 200 °C 3: 81 percent / H2SO4, HNO3 / 3 h / Ambient temperature View Scheme
参考文献
Pickert, Martina; Frahm, August Wilhelm
Archiv der Pharmazie, 1998 , vol. 331, # 5 p. 177 - 192
反应条件
copper(I) oxide; sodium methylate
T=180°C; 1 h;
参考文献
Filippatos; Papadaki-Valiraki; Roussakis; Verbist
Archiv der Pharmazie, 1993 , vol. 326, # 8 p. 451 - 456
反应条件
hydrogenchloride; potassium carbonate; copper monoiodide in N-methyl-acetamide; sodium hydroxide
参考文献
E. I. Du Pont de Nemours and Company
Patent: US5128355 A1, 1992 ;
US 5128355 A
反应条件
trifluoroacetic acid in chloroform-d1
T=100°C;
参考文献
Cella, James A.
Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 2099 - 2103
反应条件
sodium methylate; copper
T=180 - 200°C; 24 h;
参考文献
Hellwinkel, Dieter; Bohnet, Siegbert
Chemische Berichte, 1987 , vol. 120, p. 1151 - 1174
反应条件
(i) K2CO3, PhNO2, (ii) /BRN= 1305151/; Multistep reaction;
参考文献
Seidlova,V. et al.
Collection of Czechoslovak Chemical Communications, 1969 , vol. 34, # 8 p. 2258 - 2277
反应条件
methanol; sodium methylate; copper
参考文献
Cadogan; Hutchison; McNab
Tetrahedron, 1992 , vol. 48, # 36 p. 7747 - 7762
反应条件
1: 86 percent / aq. KOH / methanol
2: 85 percent / trifluoroacetic acid / CDCl3 / 100 °C
View Scheme
参考文献
Cella, James A.
Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 2099 - 2103
