2-甲基-3-吲哚乙酸乙酯合成路线 （共 22 条）
反应条件
1.1: COCl2; DMF / toluene; CH2Cl2 / 20 °C
2.1: K-Selectride / tetrahydrofuran
2.2: tetrahydrofuran / 20 °C
3.1: 98 percent / Bu3SnH; AIBN / toluene / Heating
View Scheme
参考文献
Bowman, W. Russell; Fletcher, Anthony J.; Lovell, Peter J.; Pedersen, Jan M.
Synlett, 2004 , # 11 p. 1905 - 1908
参考文献
Sengupta, Anil K.; Gupta, Anurag Ateet
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 3 p. 263 - 266
反应条件
1: 1.) triton B, 2.) conc. HCl / 1.) THF, reflux, 10 h, 2.) aq. ethanol, room temp., 1 h
2: conc.H2SO4 / 1 h / Heating
View Scheme
参考文献
Garuti; Giovanninetti; Bova; Chiarini
Archiv der Pharmazie, 1988 , vol. 321, # 7 p. 377 - 383
反应条件
1: 89 percent / 2 h / Heating
2: 60 percent / methanol / 6 h / Heating
View Scheme
参考文献
Vlaovic, Djordje; Cetkovic, Gordana; Juranic, Ivan; Balaz, Jelica; Lajsic, Stevan; Djokovic, Dejan
Monatshefte fuer Chemie, 1990 , vol. 121, # 11 p. 931 - 939
参考文献
Hoshino; Shimodaira
Justus Liebigs Annalen der Chemie, 1935 , vol. 520, p. 19,26
反应条件
1: 65 percent / N2H4*H2O / ethanol / 10 h / Heating
2: 74 percent / ethanol / Heating
3: 67 percent / 4N NaOH / 2 h / Heating
View Scheme
参考文献
Sengupta, Anil K.; Gupta, Anurag Ateet
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 3 p. 263 - 266
反应条件
1: 65 percent / N2H4*H2O / ethanol / 10 h / Heating
2: 74 percent / ethanol / Heating
View Scheme
参考文献
Sengupta, Anil K.; Gupta, Anurag Ateet
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 3 p. 263 - 266
反应条件
1: 65 percent / N2H4*H2O / ethanol / 10 h / Heating
2: 88 percent / ethanol / Heating
3: 84 percent / 4N NaOH / 2 h / Heating
View Scheme
参考文献
Sengupta, Anil K.; Gupta, Anurag Ateet
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 3 p. 263 - 266
反应条件
1: 65 percent / N2H4*H2O / ethanol / 10 h / Heating
2: 72 percent / ethanol / Heating
3: 65 percent / 4N NaOH / 2 h / Heating
View Scheme
参考文献
Sengupta, Anil K.; Gupta, Anurag Ateet
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 3 p. 263 - 266
反应条件
1: 65 percent / N2H4*H2O / ethanol / 10 h / Heating
2: 81 percent / ethanol / Heating
3: 69 percent / 4N NaOH / 2 h / Heating
View Scheme
参考文献
Sengupta, Anil K.; Gupta, Anurag Ateet
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 3 p. 263 - 266
