1: K2CO3 / dimethylformamide / 3 h / Heating 2: conc.HCl / acetic acid / 1.42 h / Ambient temperature 3: pyridine / 2 h / 120 °C 4: KOH, pyridine / 4 h / 60 °C 5: 98 percent / sodium acetate / acetic acid / 4 h / 140 °C 6: 80 percent / H2 / 10percent Pd/C / ethyl acetate; methanol 7: AlBr3 / acetonitrile / 50 °C View Scheme

1: K2CO3 / dimethylformamide / 3 h / Heating 2: conc.HCl / acetic acid / 1.42 h / Ambient temperature 3: pyridine / 2 h / 120 °C 4: KOH, pyridine / 4 h / 60 °C 5: 97 percent / sodium acetate / acetic acid / 4 h / 140 °C 6: 91 percent / H2 / 10percent Pd/C / ethyl acetate; methanol 7: AlBr3 / acetonitrile / 50 °C View Scheme

potassium carbonate in N,N-dimethyl-formamide 3 h; Heating;

1: K2CO3 / dimethylformamide / 3 h / Heating 2: conc.HCl / acetic acid / 1.42 h / Ambient temperature 3: pyridine / 2 h / 120 °C 4: KOH, pyridine / 4 h / 60 °C 5: 98 percent / sodium acetate / acetic acid / 4 h / 140 °C 6: 97 percent / H2 / 10percent Pd/C / ethyl acetate; methanol View Scheme

1: K2CO3 / dimethylformamide / 3 h / Heating 2: conc.HCl / acetic acid / 1.42 h / Ambient temperature 3: pyridine / 2 h / 120 °C 4: KOH, pyridine / 4 h / 60 °C 5: 86 percent / sodium acetate / acetic acid / 4 h / 140 °C 6: 92 percent / H2 / 10percent Pd/C / ethyl acetate; methanol 7: AlBr3 / acetonitrile / 50 °C View Scheme

1: K2CO3 / dimethylformamide / 3 h / Heating 2: conc.HCl / acetic acid / 1.42 h / Ambient temperature 3: pyridine / 2 h / 120 °C 4: KOH, pyridine / 4 h / 60 °C 5: 86 percent / sodium acetate / acetic acid / 4 h / 140 °C 6: 92 percent / H2 / 10percent Pd/C / ethyl acetate; methanol 7: AlBr3 / acetonitrile / 50 °C View Scheme

1: K2CO3 / dimethylformamide / 3 h / Heating 2: conc.HCl / acetic acid / 1.42 h / Ambient temperature 3: pyridine / 2 h / 120 °C 4: KOH, pyridine / 4 h / 60 °C 5: 98 percent / sodium acetate / acetic acid / 4 h / 140 °C 6: 97 percent / H2 / 10percent Pd/C / ethyl acetate; methanol 7: 98 percent / AlCl3 / acetonitrile / 10 h / 70 °C View Scheme

1: K2CO3 / dimethylformamide / 3 h / Heating 2: conc.HCl / acetic acid / 1.42 h / Ambient temperature View Scheme