219763-81-2合成路线

参考文献

GLAXO GROUP LIMITED
Patent: WO2007/16610 A2, 2007 ;
Location in patent: Page/Page column 32 ;

2033-24-1米氏酸+

873-74-5对氨基苯腈+

149-73-5原甲酸三甲酯

219763-81-2

参考文献

GLAXO GROUP LIMITED
Patent: WO2004/2490 A2, 2004 ;
Location in patent: Page/Page column 39 ;

15568-85-15-(甲氧基甲烯基)-2,2-二甲基-1,3-二氧己环-4,6-二酮+

873-74-5对氨基苯腈

219763-81-2

参考文献

Hill, Lawrence; Imam, S. Haider; McNab, Hamish; O'Neill, William J.
Synlett, 2009 , # 11 p. 1847 - 1851

2033-24-1米氏酸

219763-81-2

参考文献

Madrid, Peter B.; Sherrill, John; Liou, Ally P.; Weisman, Jennifer L.; DeRisi, Joseph L.; Guy, R. Kiplin
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 4 p. 1015 - 1018

219763-81-2

642477-81-4

参考文献

Lengyel, Laszlo; Nagy, Tibor Zs.; Sipos, Gellert; Jones, Richard; Dorman, Gyoergy; Uerge, Laszlo; Darvas, Ferenc
Tetrahedron Letters, 2012 , vol. 53, # 7 p. 738 - 743

219763-81-2

219763-83-44-氯-6-氰基喹啉

参考文献

Madrid, Peter B.; Sherrill, John; Liou, Ally P.; Weisman, Jennifer L.; DeRisi, Joseph L.; Guy, R. Kiplin
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 4 p. 1015 - 1018