2-氨基-4,5-二氟苯甲腈合成路线 （共 3 条）
反应条件
sodium dithionite; water in ethanol Reflux;
参考文献
KALYPSYS, INC.; BORCHARDT, Allen; DAVIS, Robert; BEAUREGARD, Clay; BECKER, Daniel; GAMACHE, Daniel; NOBLE, Stewart, A.; HELLBERG, Mark, R.; KLIMKO, Peter, G.; ZHIHAI, Qui; PAYNE, Joseph, E.; YANNI, John
Patent: WO2011/112731 A2, 2011 ;
Location in patent: Page/Page column 136-137 ;
WO 2011/112731 A2
反应条件
1.1: thionyl chloride / 1 h / Reflux 1.2: 2 h / 0 °C 2.1: triethylamine; trifluoroacetic anhydride / dichloromethane / 1 h / 20 °C 3.1: water; sodium dithionite / ethanol / Reflux View Scheme
参考文献
WO2011/112731 A2, ;
WO 2011/112731 A2
反应条件
1: triethylamine; trifluoroacetic anhydride / dichloromethane / 1 h / 20 °C 2: water; sodium dithionite / ethanol / Reflux View Scheme
参考文献
WO2011/112731 A2, ;
WO 2011/112731 A2
