反应条件
1: (S)-(-)-4-[4-(dimethylamino)-l-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile, hemi (+)-di-p-toluoyl-D-tartaric acid salt With ammonia in dichloromethane; water pH=9; 2: With triethylamine; p-toluenesulfonyl chloride in dichloromethane T=5°C; 1 h; 3: oxalic acid in acetone