1: With potassium carbonate; tri[2-(2-methoxyethoxy)ethyl]amine in dichloromethane; water 6 h; Heating / reflux; 2: With water; hydrogenchloride in tetrahydrofuran T=20°C; 2 h; 3: With sodium hydroxide in tetrahydrofuran; water T=0°C;
参考文献
Henninger, Todd C.; Macielag, Mark J.; Marinelli, Brett A.; Zhu, Bin
Patent: US2004/18994 A1, 2004 ;
Location in patent: Page/Page column 59 ;