3,5-二甲基-2-吡咯甲醛合成路线 （共 24 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); caesium carbonate in tetrahydrofuran
T=100°C; 1 h; Inert atmosphereMicrowave irradiation; stereoselective reaction;
参考文献
Lubkoll, Jana; Millemaggi, Alessia; Perry, Alexis; Taylor, Richard J.K.
Tetrahedron, 2010 , vol. 66, # 33 p. 6606 - 6612
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Treibs; Derra-Scherer
Justus Liebigs Annalen der Chemie, 1954 , vol. 589, p. 188,194
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane
Heating;
参考文献
LEO PHARMA A/S
Patent: WO2005/58309 A1, 2005 ;
Location in patent: Page/Page column 62 ;
反应条件
sulfuric acid; potassium nitrate
T=-8 - 20°C; 0.666667 h;
参考文献
Zhang, Long; Zheng, Qingmei; Yang, Yingying; Zhou, Haojie; Gong, Xingjiang; Zhao, Shuyong; Fan, Chuanwen
European Journal of Medicinal Chemistry, 2014 , vol. 82, p. 139 - 151
