1-(2-丙烯-1-基)-2(1H)-吡啶酮合成路线 （共 9 条）
反应条件
sodium iodide in acetonitrile T=50°C; Alkylation;
参考文献
Bowman, W. Russell; Bridge, Colin F.
Synthetic Communications, 1999 , vol. 29, # 22 p. 4051 - 4059
反应条件
Pd0(tris(tert-butyl)phosphine)2 in xylene T=80°C; Claisen rearrangement; 2 h; Product distribution; Further Variations:ReagentsTemperaturesSolventsreaction times;
参考文献
Itami, Kenichiro; Yamazaki, Daisuke; Yoshida, Jun-Ichi
Organic Letters, 2003 , vol. 5, # 12 p. 2161 - 2164
反应条件
bis(acetylacetonato) palladium; triphenylphosphine in tetrahydrofuran 16 h; Ambient temperature;
参考文献
Moreno-Manas; Pleixats; Villarroya
Tetrahedron, 1993 , vol. 49, # 7 p. 1457 - 1464
反应条件
in acetonitrile T=80°C; 24 h; Inert atmosphere; regioselective reaction;
参考文献
Heller, Stephen T.; Sarpong, Richmond
Tetrahedron, 2011 , vol. 67, # 46 p. 8851 - 8859
反应条件
1: 2-hydroxy-pyridine With potassium hydroxide T=25°C; 0.5 h; Ionic liquidInert atmosphere; 2: 3-chloroprop-1-ene T=25°C; 5 h; Ionic liquidInert atmosphere; Reagent/catalystSolvent;
参考文献
Vavilina; Zicmanis; Mekss; Klavins
Chemistry of Heterocyclic Compounds, 2008 , vol. 44, # 5 p. 549 - 558
Khim. Geterotsikl. Soedin., 2008 , # 5 p. 699 - 710
反应条件
1: 2-hydroxy-pyridine With sodium methylate T=25°C; 0.5 h; Ionic liquidInert atmosphere; 2: 3-chloroprop-1-ene T=25°C; 5 h; Ionic liquidInert atmosphere; Reagent/catalystSolvent;
参考文献
Vavilina; Zicmanis; Mekss; Klavins
Chemistry of Heterocyclic Compounds, 2008 , vol. 44, # 5 p. 549 - 558
Khim. Geterotsikl. Soedin., 2008 , # 5 p. 699 - 710
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Lysakowska, Magdalena; Balzarini, Jan; Piotrowska, Dorota G.
Archiv der Pharmazie, 2014 , vol. 347, # 5 p. 341 - 353
参考文献
Michant'ew et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 1874;engl.Ausg.S.1844
反应条件
ethanol; nickel
Hydrogenation;
参考文献
Michant'ew et al.
Zhurnal Obshchei Khimii, 1959 , vol. 29, p. 1874;engl.Ausg.S.1844
