1: PdCl2 / dioxane; H2O / 3 h / 60 °C 2: 89.5 percent / NaBH4 / methanol / 0.5 h / -78 °C 3: NaOH / methanol / 12 h / 20 °C 4: 14.8 mg / H2 / Pd(OH)2/C / methanol / 24 h / 20 °C View Scheme

1: PdCl2 / dioxane; H2O / 3 h / 60 °C 2: 96.3 percent / NaBH4 / methanol / 0.5 h / 0 °C 3: NaOH / methanol / 12 h / 20 °C 4: 12.4 mg / H2 / Pd(OH)2/C / methanol / 24 h / 20 °C View Scheme