3-氧代-3-(4-甲苯基)丙酸甲酯合成路线 （共 8 条）
反应条件
1: carbonic acid dimethyl ester With sodium hydride T=20°C; Inert atmosphere; 2: para-methylacetophenone 4 h; Inert atmosphereReflux;
参考文献
Chemical Communications, , vol. 47, # 39 p. 11143 - 11145
反应条件
1: 4-methyl-benzoic acid With 1,1'-carbonyldiimidazole in tetrahydrofuran T=20°C; 10 h; 2: magnesium salt of monomethyl malonic acid in tetrahydrofuran T=20°C; 18 h; Further stages.;
参考文献
Advanced Synthesis and Catalysis, , vol. 345, # 1-2 p. 261 - 274
反应条件
palladium(II) 2,4-pentanedionate; tributyl-amine; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene T=90°C; P=7500.75 Torr; 15 h; Inert atmosphereAutoclaveSchlenk technique;
参考文献
Advanced Synthesis and Catalysis, , vol. 354, # 16 p. 3105 - 3114,10
反应条件
1: Br2 / CCl4 / 1 h / -10 °C 2: triethylamine / benzene / 2 h / Heating 3: 27 percent / CH3ONa / 2 h / Ambient temperature; quenching by water View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, p. 133 - 138
反应条件
1: triethylamine / benzene / 2 h / Heating 2: 27 percent / CH3ONa / 2 h / Ambient temperature; quenching by water View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, p. 133 - 138
反应条件
triethylamine 2 h; Ambient temperature;
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, p. 133 - 138
反应条件
sodium methylate 2 h; Ambient temperaturequenching by water;
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, p. 133 - 138
反应条件
1: 95 percent / 0.17 h / 100 °C / sealed tube 2: 50 percent / triethylamine / 2 h / Ambient temperature View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, p. 133 - 138
