1: cyanomethylphosphonic acid ethyl ester With potassium tert-butylate in tetrahydrofuran
T=0 - 20°C;
2: pentanal in tetrahydrofuran
T=20°C;
3: With water in tetrahydrofuran
参考文献
INCYTE CORPORATION; LI, Yun-Long; RODGERS, James D.
Patent: WO2010/135621 A1, 2010 ;
Location in patent: Page/Page column 33-34 ;
WO 2010/135621 A1
NiBr2(PPh3)2; triphenylphosphine; zinc in N,N-dimethyl-formamide
T=50°C; 8 h;
参考文献
Sakakibara, Yasumasa; Enami, Hiroji; Ogawa, Hiroshi; Fujimoto, Shinpei; Kato, Hiroyuki; et al.
Bulletin of the Chemical Society of Japan, 1995 , vol. 68, # 11 p. 3137 - 3144
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene
T=50°C; influence of n-BuSnH concentration on ratio of product studied; Product distribution;
参考文献
Park, Seung-Un; Chung, Sung-Kee; Newcomb, Martin
Journal of the American Chemical Society, 1986 , vol. 108, # 2 p. 240 - 244
