4-溴-2-甲基苯甲酸乙酯合成路线 （共 4 条）
反应条件
thionyl chloride 3 h; Reflux;
参考文献
PFIZER INC.; HUMPHRIES, Paul, Stuart; PRICE, David, Anthony
Patent: WO2010/103429 A1, 2010 ;
Location in patent: Page/Page column 32 ;
WO 2010/103429 A1
反应条件
concentrated sulfuric acid in ethanol
参考文献
MITSUBISHI TANABE PHARMA CORPORATION
Patent: US2012/196824 A1, 2012 ;
反应条件
sulfuric acid T=100°C; Inert atmosphere;
参考文献
ALMIRALL, S.A.; GRIMA POVEDA, Pedro Manuel; AGUILAR IZQUIERDO, Nuria; MIR CEPEDA, Marta; LOPEZ MARTINEZ, Manuel
Patent: WO2010/43377 A1, 2010 ;
Location in patent: Page/Page column 81 ;
WO 2010/043377 A1
参考文献
Ube Industries, Ltd.
Patent: US6265418 B1, 2001 ;
