1: 54 percent / DEAD, n-Bu3P / tetrahydrofuran / 42 h / Ambient temperature 2: 1.) n-BuLi, 2.) CuCN-TMEDA, 3.) O2 3: 90 percent / H2 / 10percent Pd/C / ethyl acetate / 12 h 4: 92 percent / pyridine / 8 h / 0 °C 5: 96 percent / NaI / acetone / 3 h / Heating 6: Zn, EtOH / 1 h / Heating 7: 93 percent / pyridine / 2 °C 8: 68 percent / TiCl4 / benzene / 4 h / Heating 9: 85 percent / pyridine, 4-DMAP / 8 h / 50 °C 10: t-BuOK / 2-methyl-propan-2-ol / 2 h / 60 °C 11: 1.) NaH / 1.) HMPA, RT, 2.) HMPA, RT, 20 min View Scheme