(R)-3-(Fmoc-氨基)-3-苯基丙氨酸合成路线 （共 3 条）
反应条件
sodium carbonate in water; acetone
参考文献
Terracciano, Stefania; Bruno, Ines; D'Amico, Elisabetta; Bifulco, Giuseppe; Zampella, Angela; Sepe, Valentina; Smith, Charles D.; Riccio, Raffaele
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 13 p. 6580 - 6588
反应条件
1.1: Fmoc-Cl; N-methylmorpholine / tetrahydrofuran / 0.17 h / -15 °C 1.2: 86 percent / tetrahydrofuran; diethyl ether / 0 - 20 °C 2.1: 82 percent / silver benzoate / dioxane; H2O / 0.02 h / microwave irradiation View Scheme
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 43, # 10 p. 2152 - 2158
反应条件
1: NEt3 / tetrahydrofuran / 0.25 h / -15 °C 2: tetrahydrofuran; diethyl ether / 3 h / Ambient temperature 3: silver benzoate, H2O / dioxane / Ambient temperature View Scheme
参考文献
Synthesis, , # 6 p. 837 - 841
