N-(2-氯乙基)六亚甲二胺合成路线 （共 5 条）
反应条件
thionyl chloride; benzene
参考文献
Journal of the American Chemical Society, , vol. 80, p. 3729,3730
US2735847 , ;
US2743269 , ;
反应条件
1: KOH / acetonitrile / Ambient temperature 2: SOCl2, 4-DMAP / CHCl3 / 2 h / Ambient temperature View Scheme
参考文献
Archiv der Pharmazie, , vol. 328, # 7-8 p. 585 - 594
反应条件
1: potassium carbonate; caesium carbonate / acetonitrile / 24 h / 90 °C 2: thionyl chloride / tetrahydrofuran / 6 h / |Reflux View Scheme
参考文献
Wang, Chengming; Sun, Huan; Fang, Yan; Huang, Yong
Angewandte Chemie - International Edition, 2013 , vol. 52, # 22 p. 5795 - 5798
Angew. Chem., 2013 , p. 5999
反应条件
potassium carbonate; caesium carbonate in acetonitrile T=90°C; 24 h;
参考文献
Wang, Chengming; Sun, Huan; Fang, Yan; Huang, Yong
Angewandte Chemie - International Edition, 2013 , vol. 52, # 22 p. 5795 - 5798
Angew. Chem., 2013 , p. 5999
参考文献
Roxburgh; Ganellin; Athmani; Bisi; Quaglia; Benton; Shiner; Malik-Hall; Haylett; Jenkinson
Journal of Medicinal Chemistry, 2001 , vol. 44, # 20 p. 3244 - 3253
