(2S)-1-苄基-2-异丙基哌嗪合成路线 (共 2 条)
反应条件
tetra-(n-butyl)ammonium iodide; sodium hydride in N,N-dimethyl-formamide T=0 - 20°C;
参考文献
Ishida, Yasuhiro; Aida, Takuzo
Journal of the American Chemical Society, 2002 , vol. 124, # 47 p. 14017 - 14019
反应条件
hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal 1.) CH2Cl2, overnight, 2.) MeOH, 35 psi, 14 h; Yield given. Multistep reaction;
参考文献
Buenadicha, Felix L.; Avendano, Carmen; Soellhuber, Monica
Tetrahedron Asymmetry, 1998 , vol. 9, # 23 p. 4275 - 4284