5,5-二甲氧基-1,2,3,4-四氯环戊二烯合成路线 （共 20 条）
反应条件
1: petroleum ether 2: Li / tetrahydrofuran; 2-methyl-propan-2-ol 3: aq. HClO4 / tetrahydrofuran View Scheme
参考文献
Haywood-Farmer,J.S.; Pincock,R.E.
Journal of the American Chemical Society, 1969 , vol. 91, # 11 p. 3020 - 3028
反应条件
2: KOtBu / 2-methyl-propan-2-ol View Scheme
参考文献
Hoffmann,R.W.; Haeuser,H.
Tetrahedron, 1965 , vol. 21, p. 891 - 902
参考文献
Hoffmann,R.W.; Haeuser,H.
Tetrahedron, 1965 , vol. 21, p. 891 - 902
反应条件
1: FeCl3, Cl2
2: NaOMe
3: aq. H2SO4
View Scheme
参考文献
McBee,E.T. et al.
Journal of the American Chemical Society, 1962 , vol. 84, p. 3557 - 3561
反应条件
1: KOH
2: methanol / Heating
3: aq. H2SO4
View Scheme
参考文献
McBee,E.T. et al.
Journal of the American Chemical Society, 1962 , vol. 84, p. 3557 - 3561
反应条件
1: 165 °C
2: Zn
View Scheme
参考文献
Mackenzie,K.
Journal of the Chemical Society, 1962 , p. 457 - 463
反应条件
1: 24 percent / ethanol / 72 h / Heating
2: 77 percent / NaOEt / Heating; other base, var. solvents and reagents
3: KOH / ethanol; H2O / Heating
View Scheme
参考文献
Thompson, Hugh W.; Wong, Jesse K.
Journal of Organic Chemistry, 1985 , vol. 50, # 3 p. 404 - 406
反应条件
2: Na / tetrahydrofuran
3: 5percent H2SO4
4: NaBH4 / methanol
5: hydrogen / 5percent Pd-C
7: NaOCH3 / methanol
9: TsOH / benzene
View Scheme
参考文献
Menger, F. M.; Glass, L. E.
Journal of the American Chemical Society, 1980 , vol. 102, # 16 p. 5404 - 5406
参考文献
Lemal,D.M. et al.
Journal of the American Chemical Society, 1966 , vol. 88, p. 582 - 600
反应条件
1: 1.) 160 deg C, 10 h, 2.) room temperature, 16 h; reflux, 10 min
2: 70 g / Zn, AcOH / 18 h
3: 10 percent / p-TsOH / 3 h / Heating
View Scheme
参考文献
Jones, David W.; Sunko, Dionis E.; Thornton-Pett, Mark
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 6 p. 721 - 724
