2-甲氧基-3-甲基-[1,4]苯并喹啉酮合成路线 （共 30 条）
反应条件
1: (i) Ac2O, H2SO4, (ii) Py, (iii) aq. NaOH, MeOH 2: aq. NaOH 3: (KO3S)2NO, aq. NaOAc View Scheme
参考文献
Wessely,F. et al.
Monatshefte fuer Chemie, 1964 , vol. 95, p. 649 - 670
反应条件
Catalyst M-Chromium oxide; sulfuric acid
参考文献
Majima; Okazaki
Chemische Berichte, 1916 , vol. 49, p. 1490
反应条件
1: ethanol / 15 h / 20 °C 2: 14.10 g / K2CO3 / acetone / 48 h / Heating 3: 88 percent / trifluoroacetic acid / CH2Cl2 / 3 h / 20 °C View Scheme
参考文献
Nicolaou; Vassilikogiannakis; Maegerlein; Kranich
Chemistry (Weinheim an der Bergstrasse, Germany), 2001 , vol. 7, # 24 p. 5359 - 5371
反应条件
sodium dithionite in diethyl ether T=20°C; 0.5 h;
参考文献
Siddiqi, Shahzad A.; Heckrodt, Thilo J.
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2003 , vol. 58, # 4 p. 328 - 331
反应条件
T=110°C; Cycloaddition; 1 h;
参考文献
Kesteleyn, Bart; De Kimpe, Norbert
Journal of Organic Chemistry, 2000 , vol. 65, # 3 p. 635 - 639
参考文献
Majima; Okazaki
Chemische Berichte, 1916 , vol. 49, p. 1490
反应条件
1: 83 percent / methanol / 1 h / 25 °C
2: 73 percent / Cu(OAc)2 / Pd(OAc)2 / acetic acid / 19 h / 117 °C
3: 41 percent / tetrahydrofuran / -78 - 25 °C
View Scheme
参考文献
Knoelker, Hans-Joachim; Froehner, Wolfgang
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 2 p. 173 - 175
反应条件
1: 78 percent / methanol / 1 h / 25 °C
2: 83 percent / Pd(OAc)2 / acetic acid / 5 h / 117 °C
3: 71 percent / tetrahydrofuran / -78 - 25 °C
View Scheme
参考文献
Knoelker, Hans-Joachim; Froehner, Wolfgang
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 2 p. 173 - 175
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Botha, Marc E.; Giles, Robin G. F.; Yorke, Selwyn C.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 1 p. 85 - 88
反应条件
2: aq. NaOH
View Scheme
参考文献
Giles,R.G.F.; Roos,G.H.P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1976 , p. 2057 - 2060
