N,N-二异丙基氨基硼烷合成路线 （共 54 条）
反应条件
1: tBuCH2CH2B(H)NiPr2; phenyl-magnesium bromide in tetrahydrofuran T=0°C; 1 h; Inert atmosphere; 2: water With hydrogenchloride in tetrahydrofuran T=0°C; 0.583333 h; Inert atmosphere;
参考文献
Bailey, Christopher L.; Murphy, Chris L.; Clary, Jacob W.; Eagon, Scott; Gould, Naomi; Singaram, Bakthan
Heterocycles, 2012 , vol. 86, # 1 p. 331 - 341
反应条件
1: tBuCH2CH2B(H)NiPr2; Br-BDT With biscyclopentadienyliron(II) in acetonitrile T=20°C; 2.5 h; 2: With methanol in acetonitrile T=0 - 20°C; 1 h; 3: 2,3-dimethylbutane-2,3-diol in diethyl ether; acetonitrile T=20°C; 4 h; Reagent/catalyst;
参考文献
UNIVERSITE DE BORDEAUX 1; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; PUCHEAULT, Mathieu Jonathan Damien; MARCIASINI, Ludovic Daniel Alain; VAULTIER, Michel
Patent: WO2014/9169 A1, 2014 ;
Location in patent: Page/Page column 64 ;
反应条件
1: 1-bromo-4-methoxy-benzene; tBuCH2CH2B(H)NiPr2 With magnesium in tetrahydrofuran T=65°C; 4 h; Inert atmosphere; 2: water With hydrogenchloride in tetrahydrofuran T=65°C; Barbier Coupling Reaction; 0.25 h; Inert atmosphere;
参考文献
Heterocycles, , vol. 86, # 1 p. 331 - 341
反应条件
1: tBuCH2CH2B(H)NiPr2; 3-Chlorobenzenediazonium tetrafluoroborate With bis(cyclopentadienyl)titanium dichloride in acetonitrile T=20°C; 2.5 h; 2: With methanol in acetonitrile T=0 - 20°C; 1 h; 3: 2,3-dimethylbutane-2,3-diol in diethyl ether; acetonitrile T=20°C; 4 h; Reagent/catalyst;
参考文献
UNIVERSITE DE BORDEAUX 1; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; PUCHEAULT, Mathieu Jonathan Damien; MARCIASINI, Ludovic Daniel Alain; VAULTIER, Michel
Patent: WO2014/9169 A1, 2014 ;
Location in patent: Page/Page column 53-54; 67-68 ;
反应条件
1: tBuCH2CH2B(H)NiPr2; 3,5-dichlorobenzenediazonium tetrafluoroborate in acetonitrile T=20°C; 2.5 h; 2: With methanol in acetonitrile T=0 - 20°C; 1 h; 3: 2,3-dimethylbutane-2,3-diol in diethyl ether; acetonitrile T=20°C; 4 h; Reagent/catalyst;
参考文献
UNIVERSITE DE BORDEAUX 1; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; PUCHEAULT, Mathieu Jonathan Damien; MARCIASINI, Ludovic Daniel Alain; VAULTIER, Michel
Patent: WO2014/9169 A1, 2014 ;
Location in patent: Page/Page column 53-54; 70-71 ;
反应条件
1: tBuCH2CH2B(H)NiPr2; 4-Iodobenzenediazonium tetrafluoroborate With Schwartz's reagent in acetonitrile T=20°C; 2.5 h; 2: With methanol in acetonitrile T=0 - 20°C; 1 h; 3: 2,3-dimethylbutane-2,3-diol in diethyl ether; acetonitrile T=20°C; 4 h; Reagent/catalyst;
参考文献
UNIVERSITE DE BORDEAUX 1; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; PUCHEAULT, Mathieu Jonathan Damien; MARCIASINI, Ludovic Daniel Alain; VAULTIER, Michel
Patent: WO2014/9169 A1, 2014 ;
Location in patent: Page/Page column 53-54; 69 ;
反应条件
1: thien-2-yl bromide; tBuCH2CH2B(H)NiPr2 With magnesium in tetrahydrofuran T=65°C; 4 h; Inert atmosphere; 2: water With hydrogenchloride in tetrahydrofuran T=65°C; Barbier Coupling Reaction; 0.25 h; Inert atmosphere;
参考文献
Bailey, Christopher L.; Murphy, Chris L.; Clary, Jacob W.; Eagon, Scott; Gould, Naomi; Singaram, Bakthan
Heterocycles, 2012 , vol. 86, # 1 p. 331 - 341
反应条件
1: tBuCH2CH2B(H)NiPr2 With iodine; magnesium T=25°C; Barbier Coupling Reaction; RefluxInert atmosphere; 2: 1-Bromonaphthalene T=65°C; 4.083 h; 3: With hydrogenchloride in water T=25 - 65°C; 0.416667 h;
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; CLARY, Jacob, W.; SINGARAM, Bakthan
Patent: WO2013/16185 A1, 2013 ;
Location in patent: Paragraph 0114-0115 ;
反应条件
1: 1-Bromonaphthalene; tBuCH2CH2B(H)NiPr2 With magnesium in tetrahydrofuran T=65°C; 4 h; Inert atmosphere; 2: water With hydrogenchloride in tetrahydrofuran T=65°C; Barbier Coupling Reaction; 0.25 h; Inert atmosphere;
参考文献
Bailey, Christopher L.; Murphy, Chris L.; Clary, Jacob W.; Eagon, Scott; Gould, Naomi; Singaram, Bakthan
Heterocycles, 2012 , vol. 86, # 1 p. 331 - 341
反应条件
1: tBuCH2CH2B(H)NiPr2; (4-Methylphenyl)-magnesium bromide in tetrahydrofuran T=0°C; 1 h; Inert atmosphere; 2: water With hydrogenchloride in tetrahydrofuran T=0°C; 0.583333 h; Inert atmosphere;
参考文献
Bailey, Christopher L.; Murphy, Chris L.; Clary, Jacob W.; Eagon, Scott; Gould, Naomi; Singaram, Bakthan
Heterocycles, 2012 , vol. 86, # 1 p. 331 - 341
