N-(4-甲氧基苯基)甘氨酸合成路线 （共 16 条）
反应条件
1: With water; sodium hydroxide in tetrahydrofuran; ethanol T=40°C; 3 h; 2: With phosphoric acid in tetrahydrofuran; ethanol; water pH=3;
参考文献
UNIVERSITY OF LEICESTER; ANDREW, Peter William; LONNEN, Rana; DAMASO, Mafalda Pires; FRICKEL, Fritz-Frieder; HIRST, Simon Christopher; DAVIES, Mark William; HAMZA, Daniel
Patent: WO2013/83975 A2, 2013 ;
Location in patent: Page/Page column 44 ;
反应条件
sodium hydroxide in water 12 h; Heating;
参考文献
Savaliya, Piyush P.; Akbari, Vikunjana K.; Modi, Jigisha A.; Patel, Keshav C.
Medicinal Chemistry Research, 2013 , vol. 22, # 12 p. 5789 - 5797
反应条件
1: With silica gel T=20°C; 0.0666667 h; microwave irradiation; 2: With sodium hydroxide in ethanol 0.166667 h; Heating;
参考文献
Azarifar, Davood; Bosra, Hassan Ghasemnejad; Zolfigol, Mohammad-Ali; Tajbaksh, Mahmood
Heterocycles, 2006 , vol. 68, # 1 p. 175 - 181
参考文献
E. R. Squibb and Sons, Inc.
Patent: US4656185 A1, 1987 ;
反应条件
1.1: sodium acetate / ethanol / Reflux 2.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 2 °C 2.2: 20 °C / pH 3 - 4 View Scheme
参考文献
University Of Leicester; The designation of the inventor has not yet been filed
Patent: EP2602248 A1, 2013 ;
反应条件
water; sodium acetate
参考文献
Coghill; Johnson
Journal of the American Chemical Society, 1925 , vol. 47, p. 191
反应条件
1: 2-bromo acetyl bromide With poly(ethylene glycol) 3400; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 2: 4-methoxy-aniline in dichloromethane T=20°C; 3: With sodium hydroxide in water T=60°C;
参考文献
Hu, Chunling; Chen, Zuxing; Yang, Guichun
Synthetic Communications, 2004 , vol. 34, # 2 p. 219 - 224
反应条件
T=155 - 160°C; im Stickstoffstrom;
参考文献
Halberkann
Chemische Berichte, 1921 , vol. 54, p. 1160
参考文献
Halberkann
Chemische Berichte, 1921 , vol. 54, p. 1160
参考文献
Halberkann
Chemische Berichte, 1921 , vol. 54, p. 1160
