[1,2,4]三唑-1-基乙酸合成路线 （共 7 条）
反应条件
1: in tetrahydrofuran; diethyl ether T=100°C; 0.166667 h; Microwave irradiation; 2: With sodium tetrahydroborate in tetrahydrofuran; methanol; diethyl ether 0.0833333 h;
参考文献
Gregg, Brian T.; Golden, Kathryn C.; Quinn, John F.; Wang, Hong-Jun; Zhang, Wei; Wang, Ruifang; Wekesa, Francis; Tymoshenko, Dmytro O.
Tetrahedron Letters, 2009 , vol. 50, # 27 p. 3978 - 3981
反应条件
palladium on activated charcoal; ethanol; acetyl chloride Hydrogenation;
参考文献
Acta Chemica Scandinavica (1947-1973), , vol. 9, p. 1,5
反应条件
ammonium hydroxide; hydrogen; nickel
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 8 p. 1512 - 1522
反应条件
tri-ruthenium(0)dodecacarbonyl; ammonia; N-phenyl-2-(dicyclohexylphosphino)pyrrol in 1,1-dimethylpropan-1-ol T=150°C; 20 h; Cooling with dry iceMolecular sieve; chemoselective reaction;
参考文献
Imm, Sebastian; Neubert, Lorenz; Neumann, Helfried; Beller, Matthias
Angewandte Chemie - International Edition, 2010 , vol. 49, # 44 p. 8126 - 8129
反应条件
1: NH2OH*HCl, NaOH / ethanol; H2O / 0.33 h / Heating 2: Raney Ni alloy, 2 N aq. NaOH / ethanol / 1 h / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 39, # 1 p. 181 - 183
反应条件
oxygen; 5,15,10,20-tetraphenylporphyrin; triphenylphosphine 1.) CH2Cl2, -70 deg C, irradiation, 2 h, 2.) -70 deg C, 10 min; Yield given. Multistep reaction;
参考文献
Kuo; Shih
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 1 p. 181 - 183
反应条件
1: Candida antarctica B lipase / ethyl acetate / 6 h / 30 °C 2: 1N aq. KOH / 2 h / Heating View Scheme
参考文献
Iglesias, Luis E.; Sanchez, Victor M.; Rebolledo, Francisca; Gotor, Vicente
Tetrahedron Asymmetry, 1997 , vol. 8, # 16 p. 2675 - 2677
