4,5-二溴-2-(3,4-二氟苯基)-3(2H)-哒嗪酮合成路线 （共 5 条）
反应条件
1: 3',4'-difluoroaniline With hydrogen bromide; sodium nitrite in water T=-5 - 0°C; 0.5 h; 2: With hydrogen bromide; tin(ll) chloride in water T=0°C; 2 h; 3: mucobromic acid in water T=80 - 90°C;
参考文献
Zhang, Ji; Morton, Howard E.; Ji, Jianguo
Tetrahedron Letters, 2006 , vol. 47, # 49 p. 8733 - 8735
参考文献
Abbott Laboratories
Patent: US6307047 B1, 2001 ;
反应条件
1.1: HCl; NaNO2 / H2O 1.2: SnCl2 / H2O 2.1: AcOH View Scheme
参考文献
Kerdesky, Francis A. J.; Leanna, M. Robert; Zhang, Ji; Li, Wenke; Lallaman, John E.; Ji, Jianguo; Morton, Howard E.
Organic Process Research and Development, 2006 , vol. 10, # 3 p. 512 - 517
参考文献
Zhang, Ji; Morton, Howard E.; Ji, Jianguo
Tetrahedron Letters, 2006 , vol. 47, # 49 p. 8733 - 8735
反应条件
in water Inert atmosphereReflux;
参考文献
Kerdesky, Francis A. J.; Leanna, M. Robert; Zhang, Ji; Li, Wenke; Lallaman, John E.; Ji, Jianguo; Morton, Howard E.
Organic Process Research and Development, 2006 , vol. 10, # 3 p. 512 - 517
