1-Boc-4-(2-氯嘧啶-4-基)哌嗪合成路线 （共 3 条）
反应条件
triethylamine in N,N-dimethyl-formamide T=20°C; 4 h; Product distribution / selectivity;
参考文献
Kono, Mitsunori; Matsumoto, Takahiro; Imaeda, Toshihiro; Kawamura, Toru; Fujimoto, Shinji; Kosugi, Yohei; Odani, Tomoyuki; Shimizu, Yuji; Matsui, Hideki; Shimojo, Masato; Kori, Masakuni
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 4 p. 1468 - 1478
反应条件
sodium hydrogencarbonate in ethanol
参考文献
WO2011/95196 A1, ;
Page/Page column 114 ;
WO 2011/095196 A1
反应条件
sodium hydrogencarbonate in ethanol T=100°C; 1 h; Heating / reflux; Product distribution / selectivity;
参考文献
US2005/176722 A1, ;
Page/Page column 20; 22 ;
