4-(3-氯苯基)-3-氧丁酸乙酯合成路线 （共 3 条）
反应条件
pyridine in dichloromethane T=20°C; 2 h;
参考文献
Frederick, Raphael; Robert, Severine; Charlier, Caroline; De Ruyck, Jerome; Wouters, Johan; Pirotte, Bernard; Masereel, Bernard; Pochet, Lionel
Journal of Medicinal Chemistry, 2005 , vol. 48, # 24 p. 7592 - 7603
反应条件
1: SOCl2 / 2 h / Heating 2: 3.01 g / pyridine / CH2Cl2 / 2 h / 20 °C View Scheme
参考文献
Frederick, Raphael; Robert, Severine; Charlier, Caroline; De Ruyck, Jerome; Wouters, Johan; Pirotte, Bernard; Masereel, Bernard; Pochet, Lionel
Journal of Medicinal Chemistry, 2005 , vol. 48, # 24 p. 7592 - 7603
反应条件
triethylamine; magnesium chloride 1.) CH3CN, RT, 2 h, 2.) CH3CN, a) RT, overnight, b) reflux, 2 h; Yield givenMultistep reaction;
参考文献
Mai, Antonello; Artico, Marino; Sbardella, Gianluca; Massa, Silvio; Novellino, Ettore; Greco, Giovanni; Loi, Anna Giulia; Tramontane, Enzo; Marongiu, Maria Elena; La Colla, Paolo
Journal of Medicinal Chemistry, 1999 , vol. 42, # 4 p. 619 - 627
