2-((4-氟苄基)-氨基)-乙醇合成路线 （共 5 条）
反应条件
1: With sodium hydrogencarbonate in methanol 4 h; Heating / reflux; 2: With sodium tetrahydroborate in methanol T=0 - 5°C; 2 h;
参考文献
WO2003/106440 A2, ;
Page 10-11 ;
反应条件
sodium tetrahydroborate in methanol T=5 - 20°C;
参考文献
Journal of Medicinal Chemistry, , vol. 44, # 16 p. 2555 - 2564
反应条件
1: NaHCO3 / methanol / 4 h / Heating 2: sodium borohydride / methanol / 5 - 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 44, # 16 p. 2555 - 2564
反应条件
1: 2.) conc. H2SO4 / 1.) 80 deg C, 3 h, 2.) 150 deg C, 2 h 2: CHCl3 / 2 h / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 44, # 8 p. 1484 - 1492
反应条件
sulfuric acid 1.) 80 deg C, 3 h, 2.) 150 deg C, 2 h; Multistep reaction;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 44, # 8 p. 1484 - 1492
