1.1: 85 percent / 4-aminomethylpiperidine / CH2Cl2 / 0.5 h 2.1: 72 percent / TBDMS-OBt / tetrahydrofuran / 0.5 h / 20 °C 3.1: aq. HCOOH / Pd/C / methanol / 3 h / 20 °C 3.2: 80 percent / aq. NaHCO3 / 0.33 h View Scheme

<b>Multi-step reaction with 4 steps<br /> </b>1: 86 percent / 4-aminomethylpiperidine / CH₂Cl₂ / 0.5 h<br />2: 70 percent / TBDMS-OBt / tetrahydrofuran / 0.5 h / 20 &deg;C<br />3: 81 percent / 4-aminomethylpiperidine / CH₂Cl₂ / 0.5 h<br />4: 79 percent / TBDMS-OBt / tetrahydrofuran / 0.5 h / 20 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 81 percent / 4-aminomethylpiperidine / CH₂Cl₂ / 0.5 h<br />2: 79 percent / TBDMS-OBt / tetrahydrofuran / 0.5 h / 20 &deg;C<br /> <br /> &nbsp;