溴乙酰氯合成路线

参考文献

Patel, Meena V.; Kolasa, Teodozyj; Mortell, Kathleen; Matulenko, Mark A.; Hakeem, Ahmed A.; Rohde, Jeffrey J.; Nelson, Sherry L.; Cowart, Marlon D.; Nakane, Masaki; Miller, Loan N.; Uchic, Marie E.; Terranova, Marc A.; El-Kouhen, Odile F.; Donnelly-Roberts, Diana L.; Namovic, Marian T.; Hollingsworth, Peter R.; Chang, Renjie; Martino, Brenda R.; Wetter, Jill M.; Marsh, Kennan C.; Martin, Ruth; Darbyshire, John F.; Gintant, Gary; Hsieh, Gin C.; Moreland, Robert B.; Sullivan, James P.; Brioni, Jorge D.; Stewart, Andrew O.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 25 p. 7450 - 7465

22118-09-8溴乙酰氯+

41406-00-23-氨基苯异丙醚

918408-65-8

参考文献

Patel, Meena V.; Kolasa, Teodozyj; Mortell, Kathleen; Matulenko, Mark A.; Hakeem, Ahmed A.; Rohde, Jeffrey J.; Nelson, Sherry L.; Cowart, Marlon D.; Nakane, Masaki; Miller, Loan N.; Uchic, Marie E.; Terranova, Marc A.; El-Kouhen, Odile F.; Donnelly-Roberts, Diana L.; Namovic, Marian T.; Hollingsworth, Peter R.; Chang, Renjie; Martino, Brenda R.; Wetter, Jill M.; Marsh, Kennan C.; Martin, Ruth; Darbyshire, John F.; Gintant, Gary; Hsieh, Gin C.; Moreland, Robert B.; Sullivan, James P.; Brioni, Jorge D.; Stewart, Andrew O.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 25 p. 7450 - 7465

22118-09-8溴乙酰氯+

873-74-5对氨基苯腈

92767-14-1

参考文献

Kirubakaran, Sivapriya; Gorla, Suresh Kumar; Sharling, Lisa; Zhang, Minjia; Liu, Xiaoping; Ray, Soumya S.; MacPherson, Iain S.; Striepen, Boris; Hedstrom, Lizbeth; Cuny, Gregory D.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 5 p. 1985 - 1988

1750-42-13-氨基异恶唑+

22118-09-8溴乙酰氯

92931-33-42-溴-N-(异噁唑-3-基)乙酰胺

参考文献

RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter R.
Patent: US2013/281398 A1, 2013 ;
Location in patent: Paragraph 0556; 0557 ;

1072-67-93-氨基-5-甲基异唑+

22118-09-8溴乙酰氯

92947-26-72-溴-N-(5-甲基异噁唑-3-基)乙酰胺

参考文献

RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter R.
Patent: US2013/281398 A1, 2013 ;
Location in patent: Paragraph 0549; 0550 ;

22118-09-8溴乙酰氯+

634-93-52,4,6-三氯苯胺

99468-71-0

参考文献

Patel, Meena V.; Kolasa, Teodozyj; Mortell, Kathleen; Matulenko, Mark A.; Hakeem, Ahmed A.; Rohde, Jeffrey J.; Nelson, Sherry L.; Cowart, Marlon D.; Nakane, Masaki; Miller, Loan N.; Uchic, Marie E.; Terranova, Marc A.; El-Kouhen, Odile F.; Donnelly-Roberts, Diana L.; Namovic, Marian T.; Hollingsworth, Peter R.; Chang, Renjie; Martino, Brenda R.; Wetter, Jill M.; Marsh, Kennan C.; Martin, Ruth; Darbyshire, John F.; Gintant, Gary; Hsieh, Gin C.; Moreland, Robert B.; Sullivan, James P.; Brioni, Jorge D.; Stewart, Andrew O.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 25 p. 7450 - 7465

22118-09-8溴乙酰氯+

328-74-5间二(三氟甲基)苯胺

99468-72-13,5-双(三氟甲基)-N-(溴乙酰基)苯胺

参考文献

Yang, Ting; Ferrali, Alessandro; Sladojevich, Filippo; Campbell, Leonie; Dixon, Darren J.
Journal of the American Chemical Society, 2009 , vol. 131, # 26 p. 9140 - 9141

22118-09-8溴乙酰氯+

108-42-93-氯苯胺

41964-65-22-溴-n-(3-氯苯基)乙酰胺

参考文献

Kirubakaran, Sivapriya; Gorla, Suresh Kumar; Sharling, Lisa; Zhang, Minjia; Liu, Xiaoping; Ray, Soumya S.; MacPherson, Iain S.; Striepen, Boris; Hedstrom, Lizbeth; Cuny, Gregory D.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 5 p. 1985 - 1988

22118-09-8溴乙酰氯+

66-28-4毒毛旋花子苷元

4956-18-7

参考文献

Welles et al.
Pr. Soc. exp. Biol. Med., 1947 , vol. 65, p. 218

22118-09-8溴乙酰氯+

75-07-0乙醛

5309-70-6

参考文献

Sladkow; Petrow
Zhurnal Obshchei Khimii, 1954 , vol. 24, p. 450,452;engl.Ausg.S.459,460