N6-[叔丁氧羰基]-N2-[苄氧羰基]-L-赖氨酸 4-硝基苯基酯合成路线 （共 6 条）
反应条件
dicyclohexyl-carbodiimide
参考文献
Helvetica Chimica Acta, , vol. 46, p. 1637 - 1669
Chemical and Pharmaceutical Bulletin, , vol. 29, # 9 p. 2592 - 2597
反应条件
2: DCC / ethyl acetate View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 674, p. 218 - 225
反应条件
2: DCC / ethyl acetate View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 674, p. 218 - 225
反应条件
(i) aq. citric acid, Et2O, (ii) /BRN= 1893948/, Py; Multistep reaction;
参考文献
Chemische Berichte, , vol. 97, p. 3305 - 3311
反应条件
1: 1.) H2 / 1.) Pd-C / 1.) methanol, 2.) DMFA, 1 d
2: 1.) H2 / 1.) Pd-C / 1.) methanol, 2.) DMFA, 2 d
3: 80 percent / HBr / trifluoroacetic acid / 0.33 h
View Scheme
参考文献
Lavretskaya, E. F.; Ashmarin, I. P.; Kalikhevich, V. N.; Chamorovskaya, L. T.; Balaban, P. M.; et. al.
Pharmaceutical Chemistry Journal, 1981 , vol. 15, # 1 p. 1 - 3
Khimiko-Farmatsevticheskii Zhurnal, 1981 , vol. 15, # 1 p. 20 - 23
参考文献
Bender; Begue-Canton; Blakeley; Brubacher; Feder; Gunter; Kezdy; Killheffer Jr.; Marshall; Miller; Roeske; Stoops
Journal of the American Chemical Society, 1966 , vol. 88, # 24 p. 5890 - 5913
