3-甲基-2(5H)-呋喃酮合成路线 （共 48 条）
反应条件
bromine; triethylamine 1.) CH2Cl2, 1 h, 2.) CHCl3, reflux, 4 h; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 54, # 14 p. 3439 - 3456
反应条件
hydrogenchloride in tetrahydrofuran; hexane 0.75 h;
参考文献
Boukouvalas, John; Loach, Richard P.
Journal of Organic Chemistry, 2008 , vol. 73, # 20 p. 8109 - 8112
反应条件
phosphorus; water; bromine 1.) 70 deg C, 30 min; 80 deg C, 3 h, 2.) reflux, 4 h; Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1734 - 1743
反应条件
1: MCPBA / CH2Cl2 / 3 h / 20 °C 2: DBU / CH2Cl2 / 1 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 23, # 48 p. 5083 - 5084
反应条件
sodium tetrahydroborate in tetrahydrofuran THF, 0 deg C, 45 min; room temperature, 45 min;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1734 - 1743
反应条件
1: 94 percent / t-butylhypochlorite / methanol / 0.5 h / 0 °C 2: 53 percent / aluminiumoxide, NaBH4 / diethyl ether / 1 h / Ambient temperature 3: 45 percent / zinc powder / acetic acid / 0.5 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 64, # 3 p. 775 - 786
反应条件
1: 75 percent / 2 h / 120 °C 2: 94 percent / t-butylhypochlorite / methanol / 0.5 h / 0 °C 3: 53 percent / aluminiumoxide, NaBH4 / diethyl ether / 1 h / Ambient temperature 4: 45 percent / zinc powder / acetic acid / 0.5 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 64, # 3 p. 775 - 786
反应条件
1: 53 percent / aluminiumoxide, NaBH4 / diethyl ether / 1 h / Ambient temperature 2: 45 percent / zinc powder / acetic acid / 0.5 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 64, # 3 p. 775 - 786
反应条件
1: 99 percent / sodium metaperiodate / H2O; ethanol / 12 h / 0 °C 2: acetic anhydride, p-TsOH / toluene / 1 h / Heating 3: m-chloroperbenzoic acid / CH2Cl2 / 1 h / 0 °C 4: 27 percent / pyridine / 3 h / Heating View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 54, # 3 p. 817 - 821
